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The dynamin-related protein (Drp-1) and its mitochondrial adaptor fission protein 1 (Fis-1) are the main responsible for mitochondrial fission, a process positively related to mitochondrial fragmentation and apoptosis ( in vitro and in the rat hippocampus, leading to decreased elongated mitochondria, abnormal cristae depletion, apoptosis, and consequently loss of NSPCs proliferation/differentiation balance
Among these, peptide injections and platelet-rich plasma (PRP) therapy have gained attention for their potential to accelerate healing in muscle and tendon injuries
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This method allows for targeted treatment of specific areas, making it an appealing option for those with localized hyperpigmentation